Computer issues - Screen and USB malfunctions.

[Eternal.]

So I have a few issues, one of them being my screen sometimes gets weird lines on it and freezes. The audio will make a loud noise, like a car coming to a sudden stop does except the sound of the stopping continues. Its weird. I have no pictures, but here is my setup:



Another issue I have is my mouse and keyboard go off sometimes, but only when tethering internet from my phone via USB for a few hours. Any ideas?